Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656467 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6HDAC8RAB9AALDH1A1 | |
| SCHEMBL2705651 | 0.87 | HDAC1 (0.48) | HDAC1HDAC6HDAC8RAB9AALDH1A1 | |
| SCHEMBL5659797 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6HDAC8RAB9AALDH1A1 | |
| SCHEMBL14493945 | 0.87 | HDAC1 (0.48) | HDAC1HDAC6HDAC8ALDH1A1CDK5 | |
| SCHEMBL10918996 | 0.87 | HDAC1 (0.58) | HDAC1HDAC6HDAC8RAB9AALDH1A1 | |
| SCHEMBL1809552 | 0.85 | HDAC1 (0.51) | HDAC1HDAC6HDAC8NOS1C1S | |
| SCHEMBL8222179 | 0.84 | LOXL2 (0.57) | HDAC1HDAC6HDAC8SMN1; SMN2NOS1 | |
| SCHEMBL26986062 | 0.83 | HDAC1 (0.62) | HDAC1HDAC6HDAC8RAB9AALDH1A1 | |
| SCHEMBL27923748 | 0.81 | HDAC1 (0.47) | HDAC1HDAC6RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL13680923 | 0.80 | HDAC1 (0.59) | HDAC1HDAC6HDAC8RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341414-B | flame retardant fabric | 美利肯公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-219321988-U | Blowable flexible inner catheter and catheter system | 美利肯公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116247580-A | Blowable flexible inner catheter | 美利肯公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-1805945-A | Biaryl substituted thiazoles, oxazoles and imidazoles as sodium channel blockers | MERCK & CO INC (US) | 2006-07-19 | — | — | CN | disclosed |