Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.51 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651960 | 0.87 | CTSS (0.50) | CTSSCTSLCTSKCPB2CTSB | |
| SCHEMBL5123159 | 0.86 | CTSS (0.51) | CTSSCTSLCTSK | |
| SCHEMBL5131489 | 0.78 | CTSS (0.50) | CTSSCTSLCTSKCTSBREN | |
| SCHEMBL12196294 | 0.76 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12196296 | 0.76 | CTSS (0.56) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12196307 | 0.76 | CTSS (0.53) | CTSSCTSLCTSKCTSB | |
| SCHEMBL8290883 | 0.76 | CTSS (0.48) | CTSSCTSLCTSKREN | |
| SCHEMBL5132638 | 0.76 | CTSS (0.50) | CTSSCTSLCTSK | |
| SCHEMBL2163908 | 0.75 | CTSK (0.58) | CTSSCTSLCTSK | |
| SCHEMBL12196312 | 0.75 | CTSK (0.58) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1897931-A | Inhibitors of cathepsin s | IRM LLC (BM) | 2007-01-17 | — | — | CN | disclosed |