SCHEMBL28759223

SCHEMBL28759223

Cc1ccc(Cl)c(O)c1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.69
ALDH1A1 P00352 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 2/20 0.46
DHODH Q02127 5/20 0.43
CYP3A4 P08684 4/20 0.43
CYP2C9 P11712 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C8 P10632 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2A6 P11509 1/20 0.43
CYP2C19 P33261 1/20 0.43
MAPT P10636 1/20 0.42
MAPK1 P28482 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LDHA P00338 1/20 0.40
LDHB P07195 1/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375924 0.82 DPP4 (1.00) DPP4ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL342262 0.82 DPP4 (1.00) DPP4ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL3484657 0.82 ALDH1A1 (0.50) DPP4ALDH1A1KDM4EHSD17B10CYP3A4
SCHEMBL31643742 0.82 ALDH1A1 (0.50) DPP4ALDH1A1KDM4EHSD17B10CYP3A4
SCHEMBL8090741 0.81 DPP4 (0.48) DPP4ALDH1A1KDM4EHSD17B10MAPK1
SCHEMBL4638190 0.81 ALDH1A1 (0.52) DPP4ALDH1A1KDM4EHSD17B10DHODH
SCHEMBL29113265 0.80 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL16824105 0.80 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10MAPT
SCHEMBL16619328 0.80 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10MAPT
Potassium SCHEMBL16619331 0.80 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100567235-C Hydrogenation dehalogenation method of halogenated meta-cresol compound LANXESS DEUTSCHLAND GMBH (DE) 2009-12-09 CN disclosed
CN-1898188-A Hydrogenation dehalogenation method of halogenated meta-cresol compound LANXESS DEUTSCHLAND GMBH (DE) 2007-01-17 CN disclosed