Sugi Predict

Sugi Predict / Compounds / SCHEMBL16619328

SCHEMBL16619328

SCHEMBL16619328

O=C(O)c1c(Cl)ccc(Cl)c1O.[KH].[KH]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.95
▸ ALDH1A1 P00352 6/20 0.50
▸ KDM4E B2RXH2 3/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ TTR P02766 1/20 0.43
▸ TSHR P16473 5/20 0.41
▸ CA12 O43570 1/20 0.41
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA7 P43166 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ CA14 Q9ULX7 1/20 0.41
▸ TP53 P04637 1/20 0.40
▸ AKR1C2 P52895 2/20 0.39
▸ AKR1C1 Q04828 2/20 0.39
▸ AKR1C4 P17516 1/20 0.39
▸ AKR1C3 P42330 1/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28078921 1.00 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL29375924 0.98 DPP4 (1.00) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL342262 0.98 DPP4 (1.00) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL17318752 0.95 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10TTR
Potassium SCHEMBL16619331 0.95 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL16824105 0.95 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL29113265 0.95 DPP4 (0.95) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL16702731 0.85 DPP4 (0.68) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL1903652 0.84 DPP4 (0.75) DPP4ALDH1A1KDM4EHSD17B10TTR
SCHEMBL5693505 0.84 DPP4 (0.75) DPP4ALDH1A1KDM4EHSD17B10TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452439-B1 PROCESS FOR PREPARATION OF 3,6-DICHLORO-2-METHOXYBENZOIC ACID (DICAMBA) GHARDA KEKI HORMUSJI (IN) 2025-06-11 — — EP disclosed
US-10815180-B2 Process for preparation of 3,6-dichloro-2-methoxybenzoic acid (DICAMBA) Gharda Medical and Advanced Technologies Foundation (IN) 2020-10-27 — — US disclosed
CN-106458809-B Process for preparing 2, 5-dihalophenols 巴斯夫欧洲公司 2020-06-09 — — CN disclosed
US-20190119189-A1 Process for preparation of 3,6-Dichloro-2-Methoxybenzoic Acid (DICAMBA) Gharda Medical and Advanced Technologies Foundation (IN) 2019-04-25 — — US disclosed
EP-3452439-A1 PROCESS FOR PREPARATION OF 3,6-DICHLORO-2-METHOXYBENZOIC ACID (DICAMBA) Gharda, Keki Hormusji (IN) 2019-03-13 — — EP disclosed
US-10093607-B2 Selective hydrolysis and alcoholysis of chlorinated benzenes BASF SE (DE) 2018-10-09 — — US disclosed
EP-3052462-B1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2018-08-22 — — EP disclosed
US-9988333-B2 Process for making 2,5-dihalogenated phenol BASF SE (DE) 2018-06-05 — — US disclosed
WO-2017191554-A1 PROCESS FOR PREPARATION OF 3,6-DICHLORO-2-METHOXYBENZOIC ACID (DICAMBA) GHARDA KEKI HORMUSJI (IN) 2017-11-09 — — WO disclosed
US-20170174603-A1 Process for Making 2,5-Dihalogenated Phenol BASF SE (DE) 2017-06-22 — — US disclosed
EP-3145900-A1 PROCESS FOR MAKING 2,5-DIHALOGENATED PHENOL BASF SE (DE) 2017-03-29 — — EP disclosed
EP-3052463-B1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2017-03-01 — — EP disclosed
US-20160289157-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2016-10-06 — — US disclosed
US-20160251294-A1 Process for Hydrolyzing 1,2,4-trihalobenzene BASF SE (DE) 2016-09-01 — — US disclosed
EP-3052462-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2016-08-10 — — EP disclosed
EP-3052463-A1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2016-08-10 — — EP disclosed
WO-2015177093-A1 PROCESS FOR MAKING 2,5-DIHALOGENATED PHENOL BASF SE (DE) 2015-11-26 — — WO disclosed
WO-2015082422-A2 PROCESS FOR REACTING CHEMICAL COMPOUNDS BASF SE (DE) 2015-06-11 — — WO disclosed
WO-2015049360-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES BASF SE (DE) 2015-04-09 — — WO disclosed
WO-2015049160-A1 PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE BASF SE (DE) 2015-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289157-A1 SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES ADH1C, ADH1A, ADH5 DPP4 3156/4885ALDH1A1 90/4885KDM4E 880/4885
US-10093607-B2 Selective hydrolysis and alcoholysis of chlorinated benzenes ADH1C, ADH1A, ADH5 DPP4 2828/4885ALDH1A1 87/4885KDM4E 880/4885
US-20160251294-A1 Process for Hydrolyzing 1,2,4-trihalobenzene XDH, TYR, TH DPP4 1539/4885ALDH1A1 1360/4885KDM4E 782/4885
US-10815180-B2 Process for preparation of 3,6-dichloro-2-methoxybenzoic acid (DICAMBA) DDT, DDC, DERA DPP4 261/4885ALDH1A1 423/4885KDM4E 446/4885
US-20170174603-A1 Process for Making 2,5-Dihalogenated Phenol TYR, CA4, CA6 DPP4 1073/4885ALDH1A1 951/4885KDM4E 746/4885
US-20190119189-A1 Process for preparation of 3,6-Dichloro-2-Methoxybenzoic Acid (DICAMBA) DDT, DDC, DERA DPP4 261/4885ALDH1A1 423/4885KDM4E 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.