Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244780 | 0.86 | DAO (0.52) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL3584548 | 0.86 | DAO (0.52) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL5363783 | 0.85 | DAO (0.51) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL19141142 | 0.85 | DAO (0.51) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL22919854 | 0.81 | ALOX15 (0.56) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL934234 | 0.81 | HDAC3 (0.50) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL27947601 | 0.79 | CYP1A2 (0.57) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL3589062 | 0.79 | PDE3B (0.55) | DAOHDAC3MAPTHTTALOX15 | |
| SCHEMBL252567 | 0.79 | DAO (0.54) | DAOHDAC3MAPTNPC1POLB | |
| SCHEMBL6961498 | 0.79 | DAO (0.57) | DAOHDAC3MAPTNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621155-A | Method for preparing carbamatinib | 四川科伦药物研究院有限公司 | 2022-06-14 | — | — | CN | disclosed |