Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.62 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.55 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.54 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.54 |
| ▸ | BMP1 | P13497 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | NMBR | P28336 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652289 | 1.00 | PTGER4 (0.62) | PTGER4SIRT5PADI4PADI2BMP1 | |
| SCHEMBL5654676 | 0.87 | BMP1 (0.62) | PTGER4SIRT5BMP1FOLH1NMBR | |
| SCHEMBL5652214 | 0.86 | BMP1 (0.64) | PTGER4SIRT5BMP1FOLH1NMBR | |
| SCHEMBL5653457 | 0.84 | PTGER4 (0.73) | PTGER4SIRT5FOLH1HTTSIRT2 | |
| SCHEMBL5656713 | 0.81 | PTGER4 (0.77) | PTGER4FOLH1HDAC1HDAC2HDAC3 | |
| SCHEMBL5653366 | 0.81 | PTGER4 (0.69) | PTGER4SIRT5FOLH1HTTSIRT2 | |
| SCHEMBL23574915 | 0.81 | PTGER4 (0.70) | PTGER4SIRT5FOLH1HTTSIRT2 | |
| SCHEMBL22750161 | 0.81 | PTGER4 (0.70) | PTGER4SIRT5FOLH1HTTSIRT2 | |
| SCHEMBL5652870 | 0.80 | BMP1 (0.60) | PTGER4SIRT5BMP1NMBRHDAC1 | |
| SCHEMBL5656785 | 0.79 | PTGER4 (0.64) | PTGER4SIRT5PADI4PADI2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898227-A | As prostaglandin E2Ornithine derivatives as agonists or antagonists | ASTELLAS PHARMA INC (JP) | 2007-01-17 | — | — | CN | disclosed |