Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.60 |
| ▸ | NMBR | P28336 | 2/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655249 | 0.93 | BMP1 (0.61) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL5654676 | 0.93 | BMP1 (0.62) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL5652214 | 0.86 | BMP1 (0.64) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL28763201 | 0.83 | BMP1 (0.54) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL12672467 | 0.81 | BMP1 (0.87) | BMP1NMBRMAPTLMNAMMP9 | |
| SCHEMBL28759869 | 0.80 | PTGER4 (0.62) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL5652289 | 0.80 | PTGER4 (0.62) | BMP1NMBRSIRT2SIRT1SIRT3 | |
| SCHEMBL5653166 | 0.80 | PTGER4 (0.62) | SIRT2SIRT1SIRT3PTGER4CA2 | |
| SCHEMBL5653698 | 0.80 | PTGER4 (0.55) | SIRT2SIRT1SIRT3PTGER4 | |
| SCHEMBL5654338 | 0.79 | PTGER4 (0.56) | SIRT2SIRT1SIRT3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | ASTELLAS PHARMA INC. (JP) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142638-A1 | Ornithine derivatives as prostaglandin e2 agonists or antagonists | PTGER4, OXER1, RXFP4 | BMP1 2769/4885NMBR 846/4885SIRT2 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.