SCHEMBL28760079

SCHEMBL28760079

Cc1cc(C)cc([C@@H]2COC(=O)N2CC=CCC(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.38
CETP P11597 1/20 0.33
SCD5 Q86SK9 1/20 0.32
AR P10275 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28760093 0.84 CETP (0.37) PIK3CDCETP
SCHEMBL28760119 0.83 SCD5 (0.40) PIK3CDSCD5
SCHEMBL28760109 0.79 PIK3CD (0.37) PIK3CD
SCHEMBL28760120 0.78 PIK3CD (0.62) PIK3CDAR
SCHEMBL28760121 0.74 HCRTR2 (0.52)
SCHEMBL28760090 0.70 IDH1 (0.41) PIK3CD
SCHEMBL6948748 0.68 GLS (0.42) SCD5
SCHEMBL8805649 0.65 GLS (0.40) SCD5AR
SCHEMBL14828691 0.64 PIK3CD (0.54) PIK3CD
SCHEMBL579740 0.62 AVPR1A (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478422-B Intermediate of pregabalin and preparation method thereof 上海医药工业研究院 2024-03-22 CN disclosed
CN-114478422-A Pregabalin intermediate and preparation method thereof 上海医药工业研究院 2022-05-13 CN disclosed