SCHEMBL2876009

SCHEMBL2876009

CSCC[C@H](N)C(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 9/20 0.41
RNPEP Q9H4A4 1/20 0.41
GRIK1 P39086 5/20 0.40
GRIK2 Q13002 3/20 0.40
BHMT2 Q9H2M3 1/20 0.39
GRIA4 P48058 1/20 0.38
GRIK3 Q13003 1/20 0.38
GRIK5 Q16478 1/20 0.38
SLC1A1 P43005 2/20 0.37
NOS2 P35228 2/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
SLC7A5 Q01650 1/20 0.36
SLC1A3 P43003 1/20 0.35
SLC1A2 P43004 1/20 0.35
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108278 0.90 METAP2 (0.35) BHMTRNPEPBHMT2
Hydrochloric Acid SCHEMBL8954857 0.89 METAP2 (0.35) BHMTRNPEP
SCHEMBL28013446 0.84 METAP2 (0.40) BHMTRNPEPBHMT2
SCHEMBL542056 0.83 RNPEP (0.37) BHMTRNPEPBHMT2
SCHEMBL16513337 0.83 METAP2 (0.40) BHMTRNPEPBHMT2
SCHEMBL5617582 0.82 RNPEP (0.42) BHMTRNPEPBHMT2
SCHEMBL6045793 0.82 RNPEP (0.42) BHMTRNPEPBHMT2
SCHEMBL162031 0.82 RNPEP (0.42) BHMTRNPEPBHMT2
SCHEMBL20996747 0.82 RNPEP (0.42) BHMTRNPEPBHMT2
Serine SCHEMBL5577056 0.82 RNPEP (0.37) BHMTRNPEPBHMT2SLC1A1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3243835-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-04-10 EP disclosed
US-11555061-B2 Albumin variants and conjugates ALBUMEDIX, LTD (GB) 2023-01-17 US disclosed
US-20200392206-A1 ALBUMIN VARIANTS AND CONJUGATES SARTORIUS ALBUMEDIX LIMITED (GB) 2020-12-17 US disclosed
EP-3243835-A1 ALBUMIN VARIANTS AND CONJUGATES Albumedix A/S (DK) 2017-11-15 EP disclosed
EP-2396347-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX AS (DK) 2017-04-12 EP disclosed
US-20170081389-A1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2017-03-23 US disclosed
US-9493545-B2 Albumin variants and conjugates ALBUMEDIX A/S (DK) 2016-11-15 US disclosed
US-20110313133-A1 Albumin variants and conjugates NOVOZYMES A/S (DK) 2011-12-22 US disclosed
EP-2396347-A2 ALBUMIN VARIANTS AND CONJUGATES Novozymes Biopharma DK A/S (DK) 2011-12-21 EP disclosed
WO-2010092135-A2 ALBUMIN VARIANTS AND CONJUGATES NOVOZYMES BIOPHARMA UK LTD. (GB) 2010-08-19 WO disclosed
US-6809078-B2 NUCLEOTIDE SEQUENCES CODING POLYPEPTIDE USE IN THE GENERATION OF INSECT RESISTANT PLANTS; BIOLOGICAL PEST CONTROL MONSANTO TECHNOLOGY LLC 2004-10-26 US disclosed
US-20030101482-A1 Compositions encoding lepidopteran-toxic polypeptides and methods of use MONSANTO TECHNOLOGY LLC 2003-05-29 US disclosed