Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 10/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 2/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.31 |
| ▸ | PPID | Q08752 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8954857 | 0.98 | METAP2 (0.35) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL2876009 | 0.90 | BHMT (0.41) | RNPEPBHMTBHMT2 | |
| SCHEMBL5617582 | 0.89 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL20996747 | 0.89 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL162031 | 0.89 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL6045793 | 0.89 | RNPEP (0.42) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL1828293 | 0.86 | METAP2 (0.35) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL5178597 | 0.86 | METAP2 (0.35) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL542056 | 0.86 | RNPEP (0.37) | METAP2METAP1MARS1RNPEPANPEP | |
| SCHEMBL16513337 | 0.86 | METAP2 (0.40) | METAP2METAP1MARS1RNPEPANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3061817-B1 | ALKALINE PROTEASE VARIANTS | KAO CORP (JP) | 2018-12-12 | — | — | EP | disclosed |
| EP-3061817-A1 | ALKALINE PROTEASE VARIANTS | KAO CORPORATION (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-8778650-B2 | Alkaline protease variants | KAO CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20120058928-A1 | Alkaline Protease Variants | KAO CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| EP-2424981-A2 | ALKALINE PROTEASE VARIANTS | Kao Corporation (JP) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126156-A2 | ALKALINE PROTEASE VARIANTS | KAO CORPORATION (JP) | 2010-11-04 | — | — | WO | disclosed |