⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287612 | 1.00 | — | — | |
| SCHEMBL7219713 | 1.00 | — | — | |
| SCHEMBL29222987 | 0.89 | ALDH1A1 (0.40) | — | |
| SCHEMBL164110 | 0.82 | — | — | |
| Diisopropanolamine SCHEMBL29053431 | 0.81 | CYP2D6 (0.42) | — | |
| Adipic Acid SCHEMBL14965585 | 0.81 | LMNA (0.50) | — | |
| SCHEMBL7179855 | 0.81 | KDM4E (0.41) | — | |
| SCHEMBL28833553 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL22043850 | 0.81 | ALDH1A1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL5886752 | 0.80 | CYP2D6 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775066-A | Organic selenium microbial fertilizer and preparation method thereof | 北京中农硒谷科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-12137682-B2 | Compositions and methods for reducing ice crystal formation | X-THERMA, INC. (US) | 2024-11-12 | — | — | US | claimed |
| US-20230276788-A1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | X-THERMA, INC. | 2023-09-07 | — | — | US | claimed |
| EP-3370518-B1 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | X THERMA INC (US) | 2023-08-23 | — | — | EP | claimed |
| CN-108347916-B | Composition and method for reducing ice crystal formation | 先时迈纳米生物科技股份有限公司 | 2022-02-08 | — | — | CN | claimed |
| EP-3370518-A2 | COMPOSITIONS AND METHODS FOR REDUCING ICE CRYSTAL FORMATION | X-Therma, Inc. (US) | 2018-09-12 | — | — | EP | claimed |
| CN-108347916-A | Composition and method for reducing ice crystal formation | 先时迈纳米生物科技股份有限公司 | 2018-07-31 | — | — | CN | claimed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| US-9986733-B2 | Compositions and methods for reducing ice crystal formation | X-THERMA, INC. (US) | 2018-06-05 | — | — | US | claimed |
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| WO-2011014973-A2 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2011-02-10 | — | — | WO | claimed |
| US-20080233137-A1 | Compounds that Block the C5a Receptor and Their Use in Therapy | ALLIGATOR BIOSCIENCE AB (SE) | 2008-09-25 | — | — | US | claimed |
| CN-1997664-A | Compounds that block the C5A receptor and their use in therapy | ALLIGATOR BIOSCIENCE AB PUBL (SE) | 2007-07-11 | — | — | CN | claimed |
| EP-1737886-A2 | COMPOUNDS THAT BLOCK THE C5A RECEPTOR AND THEIR USE IN THERAPY | Alligator Bioscience AB (publ) (SE) | 2007-01-03 | — | — | EP | claimed |
| WO-2005100385-A2 | COMPOUNDS THAT BLOCK THE C5A RECEPTOR AND THEIR USE IN THERAPY | ALLIGATOR BIOSCIENCE AB (PUBL) (SE) | 2005-10-27 | — | — | WO | claimed |
| EP-1586583-A2 | Compounds that block C5a complement receptor and their use in therapy | Alligator Bioscience AB (publ) (SE) | 2005-10-19 | — | — | EP | claimed |
| EP-0804181-A4 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES CAUSED BY INFLAMMATORY RESPONSE | CELLULAR SCIENCES INC (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003006048-A1 | COMBINATION OF CHIPS (CHEMOTAXIS INHIBITING PROTEIN FROM STAPHYLOCOCCUS AUREUS)-BASED COMPOUNDS | JARI PHARMACEUTICALS B.V. (NL) | 2003-01-23 | — | — | WO | claimed |
| EP-0804181-A1 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES CAUSED BY INFLAMMATORY RESPONSE | Cellular Sciences, Inc. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1997010818-A1 | METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES CAUSED BY INFLAMMATORY RESPONSE | CELLULAR SCIENCES, INC. (US) | 1997-03-27 | — | — | WO | claimed |