Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065651 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL27594634 | 0.84 | NOTUM (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL28761815 | 0.84 | MAPT (0.48) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL6617704 | 0.84 | MAPT (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL16056048 | 0.84 | NR4A2 (0.47) | ALDH1A1MAPTHSD17B10HPGDGAA | |
| SCHEMBL28752184 | 0.83 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL5832949 | 0.83 | MAPT (0.54) | KDM4EMAPTATMCA12CA1 | |
| SCHEMBL27792226 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL4278401 | 0.83 | ABL1 (0.51) | KDM4EALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL5251504 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7413727-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2008-08-19 | — | — | US | disclosed |
| EP-1442751-B1 | Diagnostic imaging technique | GE HEALTHCARE AS (NO) | 2007-06-20 | — | — | EP | disclosed |
| CN-1886376-A | Pyridine compounds as dipeptidyl dipeptidase-IV inhibitors | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| EP-1442751-A1 | Method of imaging | Amersham Health AS (NO) | 2004-08-04 | — | — | EP | disclosed |
| EP-0977600-B1 | CONTRAST AGENTS TARGETTING RECEPTORS ASSOCIATED WITH ANGIOGENESIS | AMERSHAM HEALTH AS (NO) | 2004-06-30 | — | — | EP | disclosed |
| US-20040009122-A1 | Contrast agents | AMERSHAM HEALTH AS (NO) | 2004-01-15 | — | — | US | disclosed |
| EP-0977600-A2 | CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998047541-A1 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009122-A1 | Contrast agents | FLT1, FLT4, KDR | KDM4E 4102/4885ALDH1A1 4212/4885MAPT 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.