SCHEMBL28762129

SCHEMBL28762129

NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1OC(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 20/20 0.54
CA2 P00918 20/20 0.54
CA12 O43570 16/20 0.54
CA7 P43166 16/20 0.54
CA13 Q8N1Q1 16/20 0.54
CA9 Q16790 5/20 0.43
CA3 P07451 2/20 0.37
CA4 P22748 2/20 0.37
CA6 P23280 2/20 0.37
CA5A P35218 2/20 0.37
CA14 Q9ULX7 2/20 0.37
CA5B Q9Y2D0 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24459979 0.80 CA1 (0.34) CA1CA2CA12CA7CA13
SCHEMBL29899453 0.76 CA1 (0.37) CA1CA2CA12CA7CA13
SCHEMBL22909157 0.76 GSTO1 (0.32) CA1CA2CA12CA7CA13
SCHEMBL29729037 0.76 GSTO1 (0.32) CA1CA2CA12CA7CA13
SCHEMBL24459887 0.75 CA1 (0.58) CA1CA2CA12CA7CA13
SCHEMBL31171303 0.72 CA1 (0.32) CA1CA2CA9
SCHEMBL571331 0.72 CA1 (1.00) CA1CA2CA12CA7CA13
SCHEMBL24460006 0.72 CA1 (0.54) CA1CA2CA12CA7CA13
SCHEMBL30534023 0.72 CA1 (0.54) CA1CA2CA12CA7CA13
SCHEMBL28762115 0.72 CA1 (0.54) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4017843-A1 BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF 2692372 Ontario, Inc. (CA) 2022-06-29 EP disclosed
CN-114502533-A Benzenesulfonamide derivatives and use thereof 2692372安大略公司 2022-05-13 CN disclosed