Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.76 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.76 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.76 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.76 |
| ▸ | DRD3 | P35462 | 1/20 | 0.76 |
| ▸ | XDH | P47989 | 1/20 | 0.76 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL385842 | 0.91 | LMNA (0.92) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL31591098 | 0.90 | PI4KA (0.76) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL14125908 | 0.90 | PI4KA (0.76) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL9621210 | 0.89 | PI4KA (0.81) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1331751 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29355156 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29442902 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL3414606 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL8111 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL29982697 | 0.87 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1845745-B | Use of TLR7 ligand and prodrug thereof in preparation of drugs for treating hepatitis c virus infection | ANADYS PHARMACEUTICALS INC | 2011-11-02 | — | — | CN | disclosed |
| CN-1845745-A | Administration of TLR7 ligands and prodrugs thereof for the treatment of hepatitis C virus infection | ANADYS PHARMACEUTICALS INC (US) | 2006-10-11 | — | — | CN | disclosed |