Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 3/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28763483 | 0.83 | MAPT (0.48) | ARLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL29101588 | 0.82 | LMNA (0.53) | RPA1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4172241 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTSMN1; SMN2MARS1 | |
| SCHEMBL28763471 | 0.74 | AR (0.36) | ARALDH1A1MAPTSMN1; SMN2CNR1 | |
| SCHEMBL15428691 | 0.73 | AR (0.44) | ARLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL4976151 | 0.70 | MEN1 (0.37) | RPA1ALDH1A1KDM4EMAPTCCR2 | |
| SCHEMBL29361008 | 0.69 | DHODH (0.41) | LMNARARGSMN1; SMN2 | |
| SCHEMBL535475 | 0.69 | DHODH (0.41) | LMNARARGSMN1; SMN2 | |
| SCHEMBL30070446 | 0.69 | LMNA (0.44) | LMNAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28960840 | 0.69 | LMNA (0.44) | LMNAALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621144-A | Cyano-substituted phenyl pyrazole amide derivative and preparation method and application thereof | 南开大学 | 2022-06-14 | — | — | CN | disclosed |