SCHEMBL28763522

SCHEMBL28763522

CC(O)OCCOCCCO

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.33
USP2 O75604 1/20 0.31
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4289883 0.86 MEN1 (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL5162479 0.86 MEN1 (0.55) MEN1KMT2ATHRBHTTMAPT
SCHEMBL7914825 0.85
SCHEMBL8057662 0.85 MEN1 (0.39) MEN1KMT2ATSHRMAPK1
SCHEMBL8069328 0.85 MEN1 (0.39) MEN1KMT2ATSHRMAPK1
SCHEMBL21069301 0.82 TSHR (0.50) MEN1KMT2ATHRBHTTMAPT
SCHEMBL1308908 0.82 TSHR (0.50) MEN1KMT2ATHRBHTTMAPT
SCHEMBL4799586 0.82 TSHR (0.50) MEN1KMT2ATHRBHTTMAPT
SCHEMBL29377792 0.80 HTT (0.54) MEN1KMT2ATHRBHTTMAPT
SCHEMBL2373764 0.79 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716296-B Efficient halogenation synthesis method of alkyl halide 润药仁智(北京)科技有限公司 2023-12-12 CN disclosed
CN-114634432-B High-efficiency synthesis method of alkyl aryl thioether compound 润药仁智(北京)科技有限公司 2023-03-14 CN disclosed
CN-114716296-A Efficient halogenation synthesis method of alkyl halide 北京大学 2022-07-08 CN disclosed
CN-114634432-A High-efficiency synthesis method of alkyl aryl thioether compound 北京大学 2022-06-17 CN disclosed