SCHEMBL4289883

SCHEMBL4289883

CC(O)OCCOCCO

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TSHR P16473 2/20 0.50
MAPK1 P28482 1/20 0.50
THRB P10828 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5162479 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL8057662 0.89 MEN1 (0.39) MEN1KMT2ATSHRMAPK1HSD17B10
SCHEMBL8069328 0.89 MEN1 (0.39) MEN1KMT2ATSHRMAPK1HSD17B10
SCHEMBL19543462 0.88 MEN1 (0.42) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL28763522 0.86 MEN1 (0.40) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL21069301 0.86 TSHR (0.50) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL17656329 0.84
Tetraethylene Glycol SCHEMBL17006462 0.84 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL765642 0.84
SCHEMBL12527310 0.83 MEN1 (0.42) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118244593-A Composition for stripping photoresist 株式会社东进世美肯 2024-06-25 CN disclosed
CN-117247238-A Nano lamellar porous calcium hydroxide and preparation method and application thereof 华北电力大学(保定) 2023-12-19 CN disclosed
CN-116194084-A Cleavable lipid compounds, compositions containing the same and uses thereof 赛诺菲巴斯德有限公司 2023-05-30 CN disclosed
CN-113614647-A Resist stripping liquid 松下知识产权经营株式会社 2021-11-05 CN disclosed
CN-113614648-A Resist stripping liquid 松下知识产权经营株式会社 2021-11-05 CN disclosed
CN-113614646-A Resist stripping liquid 松下知识产权经营株式会社 2021-11-05 CN disclosed
CN-112912376-A Proteolytic targeted chimeric (PROTAC) compounds with E3 ubiquitin ligase binding activity and targeting alpha-synuclein for the treatment of neurodegenerative diseases 阿尔维纳斯运营股份有限公司 2021-06-04 CN disclosed
CN-108495888-B Additive mixture for stabilizing polyols and polyurethanes 巴斯夫欧洲公司 2021-03-02 CN disclosed
CN-112218859-A Modulators of proteolysis and related methods of use 阿尔维纳斯运营股份有限公司 2021-01-12 CN disclosed
CN-106501043-A A kind of paraffin section method of effective observation oil palm gynoecium anatomical structure 中国热带农业科学院椰子研究所 2017-03-15 CN disclosed
EP-2508544-A1 Degradable polyacetal polymers Argon Pharma S.L. (ES) 2012-10-10 EP disclosed
US-8202901-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2012-06-19 US disclosed
CN-102271691-A Natural silver disinfectant compositions 2011-12-07 CN disclosed
US-20090258835-A1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) 2009-10-15 US disclosed
US-4508916-A Curable substituted urethane acrylates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-04-02 US disclosed
US-4477635-A Polymeric triarylmethane dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258835-A1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE GPR119, SLC2A4, SLC2A1 MEN1 3955/4885KMT2A 4588/4885TSHR 623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.