Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4289883 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL8057662 | 0.89 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL8069328 | 0.89 | MEN1 (0.39) | MEN1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL19543462 | 0.88 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL28763522 | 0.86 | MEN1 (0.40) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL21069301 | 0.86 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL17656329 | 0.84 | — | — | |
| Tetraethylene Glycol SCHEMBL17006462 | 0.84 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL765642 | 0.84 | — | — | |
| SCHEMBL12527310 | 0.83 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487762-B1 | RADIOFLUORINATION METHODS | GE HEALTHCARE LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| US-4508916-A | Curable substituted urethane acrylates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-04-02 | — | — | US | disclosed |