Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672600 | 0.83 | SLC9A1 (0.42) | ALDH1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL14142525 | 0.78 | HSP90AA1 (0.34) | ALDH1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL2673041 | 0.77 | MAPT (0.36) | THRBALDH1A1POLBMAPTBLM | |
| SCHEMBL2673890 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL2679292 | 0.76 | CYP1A2 (0.41) | ALDH1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL2673527 | 0.75 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTTDP1L3MBTL1 | |
| SCHEMBL2672706 | 0.75 | CYP2A6 (0.49) | ALDH1A1MAPTL3MBTL1PDE3BPDE3A | |
| SCHEMBL2673850 | 0.74 | S1PR1 (0.35) | ALDH1A1POLBMAPTKMT2AL3MBTL1 | |
| SCHEMBL2673813 | 0.73 | HSP90AA1 (0.38) | ALDH1A1POLBMAPTKMT2ATDP1 | |
| SCHEMBL2673206 | 0.72 | ALDH1A1 (0.41) | ALDH1A1POLBMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960975-A | Substituted pyridones as poly (ADP-ribose) polymerase (PARP) inhibitors | AVENTIS PHARMA INC (US) | 2007-05-09 | — | — | CN | claimed |
| CN-1960975-A | Substituted pyridones as poly (ADP-ribose) polymerase (PARP) inhibitors | AVENTIS PHARMA INC (US) | 2007-05-09 | — | — | CN | disclosed |