Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | GRN | P28799 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27860360 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL28767211 | 0.88 | GRN (0.61) | SMN1; SMN2POLBMAPTKMT2AMEN1 | |
| SCHEMBL27706437 | 0.88 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL4689814 | 0.83 | GRN (0.64) | SMN1; SMN2POLBMAPTKMT2AMEN1 | |
| SCHEMBL27706390 | 0.81 | MAPT (0.56) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL14144797 | 0.78 | SMN1; SMN2 (0.81) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL4690033 | 0.75 | PPARG (0.83) | PPARGPPARDPPARA | |
| SCHEMBL2565517 | 0.75 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2POLBMAPTKMT2A | |
| SCHEMBL27687138 | 0.75 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBMAPTKMT2AMEN1 | |
| SCHEMBL2546138 | 0.73 | PHGDH (0.65) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101121711-A | Pyrazolcarbazone derivatives and application thereof | UNIV SHANDONG (CN) | 2008-02-13 | — | — | CN | disclosed |
| CN-101085758-A | 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivative, preparation method and application thereof | UNIV SHANDONG (CN) | 2007-12-12 | — | — | CN | disclosed |