Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.38 |
| ▸ | KDM6B | O15054 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768185 | 0.90 | KDM4C (0.36) | MGLLKDM4CKDM6BTRPV1FFAR1 | |
| SCHEMBL28768211 | 0.86 | KDM4C (0.49) | MGLLKDM4CKDM6BCTNNB1WNT3A | |
| SCHEMBL28768092 | 0.86 | MGLL (0.42) | MGLLKDM4CKDM6BTRPV1 | |
| SCHEMBL28943661 | 0.84 | TSHR (0.42) | KDM4CKDM6BPTGDR2 | |
| SCHEMBL28768180 | 0.84 | KIF11 (0.44) | KDM4CCTNNB1WNT3ATRPV1 | |
| SCHEMBL28768183 | 0.84 | MAP3K14 (0.40) | MGLLKDM4CKDM6BKDM4EPTGDR2 | |
| SCHEMBL28768317 | 0.81 | KDM4C (0.36) | KDM4CKDM6BKDM4E | |
| SCHEMBL28768120 | 0.80 | SMYD3 (0.36) | KDM4CKDM6BCTNNB1WNT3A | |
| SCHEMBL28769309 | 0.79 | KDM4C (0.47) | MGLLKDM4CTRPV1 | |
| SCHEMBL23362309 | 0.79 | TRPV1 (0.46) | MGLLKDM4CKDM6BTRPV1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641477-B | Compounds having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | claimed |
| CN-114641477-B | Compounds having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | disclosed |