Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768377 | 0.88 | HDAC3 (0.39) | KDM4CRAB9ACTNNB1SMN1; SMN2LMNA | |
| SCHEMBL28768233 | 0.88 | MAPT (0.41) | NPC1RAB9ASMN1; SMN2MAPTTERT | |
| SCHEMBL28768179 | 0.87 | TSHR (0.43) | TSHRNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28768101 | 0.84 | TP53 (0.39) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL28769275 | 0.84 | KIF11 (0.43) | KDM4CCCR5 | |
| SCHEMBL28943632 | 0.82 | HCRTR2 (0.40) | — | |
| SCHEMBL28768216 | 0.82 | KDM4C (0.41) | KDM4CNPC1RAB9ACTNNB1WNT3A | |
| SCHEMBL28768223 | 0.82 | MAP3K14 (0.39) | NPC1RAB9ALMNAMAPTHPGD | |
| SCHEMBL28768299 | 0.82 | TSHR (0.41) | TSHRNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28768358 | 0.79 | ADRA2A (0.42) | KDM4CTSHRNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641477-B | Compounds having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | claimed |
| CN-114641477-B | Compounds having inhibitory activity on glucosylceramide synthase or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114641477-A | Novel compound having inhibitory activity against glucose ceramide synthase or pharmaceutically acceptable salt thereof, method for preparing same, and pharmaceutical composition comprising same | 柳韩洋行 | 2022-06-17 | — | — | CN | disclosed |