Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 14/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685290 | 0.78 | MAOB (0.59) | CYP1A2MAOBLMNAPTGS1SLC6A2 | |
| SCHEMBL27684770 | 0.78 | BACE1 (0.52) | MAOBMAOAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL23638550 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL561095 | 0.76 | MAOB (0.62) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL5193159 | 0.75 | CYP1A2 (0.47) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL28102855 | 0.75 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL28849620 | 0.74 | MAOB (0.49) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL27664376 | 0.73 | MEN1 (0.47) | CYP1A2CYP1A1CYP19A1MAOBLMNA | |
| SCHEMBL1734928 | 0.72 | LMNA (0.59) | CYP1A2MAOBLMNAPTGS1SLC6A2 | |
| SCHEMBL10030221 | 0.72 | CYP1A2 (0.58) | CYP1A2CYP1A1CYP19A1MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039937-A | Heteroaryl compounds for use as betamimetics in the treatment of respiratory diseases | BOEHRINGER INGELHEIM INT (DE) | 2007-09-19 | — | — | CN | disclosed |