SCHEMBL1734928

SCHEMBL1734928

Nc1cc(OCc2ccccc2)ccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ PTGS1 P23219 1/20 0.59
▸ SLC6A2 P23975 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ PTGS2 P35354 1/20 0.59
▸ SLC6A3 Q01959 1/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ HDAC6 Q9UBN7 1/20 0.59
▸ MAOB P27338 8/20 0.58
▸ MAPT P10636 2/20 0.58
▸ MAOA P21397 2/20 0.58
▸ GAA P10253 1/20 0.58
▸ RAB9A P51151 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ALOX5 P09917 1/20 0.56
▸ MCL1 Q07820 1/20 0.52
▸ NPSR1 Q6W5P4 1/20 0.52
▸ PARP10 Q53GL7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273100 0.88 LMNA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8599201 0.85 LMNA (0.68) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL30040891 0.84 MAOB (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL4473165 0.84 MAOB (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
Hydrochloric Acid SCHEMBL9124176 0.82 MAOB (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11114770 0.81 MAOB (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL2096058 0.81 LMNA (0.61) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL26604791 0.80 MAOB (0.54) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL811219 0.80 CYP1A2 (0.60) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL1532839 0.79 LMNA (0.59) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 — — US disclosed
US-20250127903-A1 SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2025-04-24 — — US disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 — — EP disclosed
CN-119730846-A Kinase modulators and methods of use thereof 神经元23公司 2025-03-28 — — CN disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 — — WO disclosed
US-12048747-B2 Substituted piperidine Degronimers for Target Protein degradation C4 THERAPEUTICS, INC. (US) 2024-07-30 — — US disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 — — US disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 — — US disclosed
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF SUNDANCE BIOSCIENCES, INC. 2024-01-25 — — US disclosed
WO-2023244788-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2023-12-21 — — WO disclosed
EP-1020451-A1 NOVEL ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-07-19 — — EP disclosed
US-5773227-A CHELATE COMPOUNDS, FLUORESCENT INDICATOR AND TARGET PEPTIDES MOLECULAR PROBES, INC. (US) 1998-06-30 — — US disclosed
EP-0193051-B1 2-EQUIVALENT CYAN DYE-FORMING 5-HYDROXY-6-ACYLAMINO-BENZOXAZOLE-2-ONE COUPLERS, SILVER HALIDE PHOTOGRAPHIC ELEMENTS AND PROCESSES EMPLOYING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-03-01 — — EP disclosed
EP-0168729-B1 CYAN DYE-FORMING COUPLERS AND PHOTOGRAPHIC ELEMENTS AND PROCESSES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-01-04 — — EP disclosed
US-4762925-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-08-09 — — US disclosed
US-4672013-A 6-HYDROXYL-2H-U,4-BENZOXAZIN-3-(4H)-ONE COUPLER REACTS WITH DEVELOPER TO GIVE INDOANILINE DYE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-06-09 — — US disclosed
US-4668610-A 2-equivalent cyan dye-forming 5-hydroxy-6-acylamino-benzoxazole-2-one couplers, silver halide photographic elements and processes employing them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-26 — — US disclosed
EP-0193051-A2 2-Equivalent cyan dye-forming 5-hydroxy-6-acylamino-benzoxazole-2-one couplers, silver halide photographic elements and processes employing them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-03 — — EP disclosed
US-4591548-A 6-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-05-27 — — US disclosed
EP-0168729-A2 Cyan dye-forming couplers and photographic elements and processes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-01-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127903-A1 SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, NEDD4 LMNA 3153/4885CYP1A2 2665/4885PTGS1 4486/4885
US-20240025906-A1 KINASE MODULATORS AND METHODS OF USE THEREOF TYK2, JAK1, JAK3 LMNA 4294/4885CYP1A2 3726/4885PTGS1 1754/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT LMNA 2684/4885CYP1A2 1677/4885PTGS1 2492/4885
US-12048747-B2 Substituted piperidine Degronimers for Target Protein degradation GID4, RNF5, UBE3C LMNA 3292/4885CYP1A2 2046/4885PTGS1 4306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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