Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225127 | 0.98 | USP2 (0.58) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL8286 | 0.98 | USP2 (0.58) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL587550 | 0.98 | USP2 (0.58) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL12005408 | 0.98 | USP2 (0.58) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL2934532 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL132585 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL2220355 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL14653343 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| Ammonia Solution, Strong SCHEMBL18035416 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL | |
| Hydrochloric Acid SCHEMBL1904026 | 0.96 | USP2 (0.56) | USP2SMN1; SMN2MAPK1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203495-A | Benzocycloheptapyridine compounds as inhibitors of receptor tyrosine kinase MET | MERCK & CO INC (US) | 2008-06-18 | — | — | CN | disclosed |