SCHEMBL28769397

SCHEMBL28769397

Brc1ccccc1Br.COC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
KMT2A Q03164 4/20 0.45
KCNN4 O15554 1/20 0.45
RAB9A P51151 4/20 0.44
MEN1 O00255 3/20 0.44
NPC1 O15118 3/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
HDAC4 P56524 1/20 0.42
AKR1C3 P42330 1/20 0.41
HDAC3 O15379 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
IDO1 P14902 1/20 0.41
ALOX15 P16050 1/20 0.41
HDAC1 Q13547 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27591824 0.81 AKR1C3 (0.52) TSHRKMT2ARAB9AMEN1NPC1
Biphenyl SCHEMBL3255863 0.79 TSHR (0.54) TSHRKMT2AKCNN4RAB9ANPC1
Naphthalene SCHEMBL28307374 0.79 TSHR (0.54) TSHRKMT2AKCNN4RAB9AMEN1
Acetone SCHEMBL27771503 0.78 AKR1C3 (0.48) KMT2ARAB9AMEN1NPC1HTT
Methoxymethane SCHEMBL28099062 0.78 ALDH1A1 (0.53) CA12CA1IDO1CA9ALDH1A1
Benzene SCHEMBL28156248 0.78 TSHR (0.48) TSHRKMT2AKCNN4RAB9ALMNA
Phenol SCHEMBL25374179 0.77 CA12 (0.58) TSHRKMT2AKCNN4HTTLMNA
Catechol SCHEMBL27621256 0.77 TSHR (0.58) TSHRKMT2AKCNN4RAB9AMEN1
Phenol SCHEMBL18603299 0.77 CA12 (0.58) TSHRKMT2AKCNN4HTTLMNA
Bicarbonate SCHEMBL20918171 0.76 TSHR (0.57) TSHRKMT2AMEN1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114667630-A Flame retardant for battery electrolytes 雅宝公司 2022-06-24 CN disclosed