Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 4/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2874583 | 0.88 | CHEK1 (0.46) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL2879621 | 0.87 | MKNK1 (0.45) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL2878830 | 0.83 | ALDH1A1 (0.42) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL5728485 | 0.82 | ALDH1A1 (0.41) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL2870746 | 0.81 | KDM4E (0.64) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL5430057 | 0.74 | CNR2 (0.55) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL3807534 | 0.74 | KDM4E (0.58) | KDM4EMAPTALDH1A1LMNAHPGD | |
| SCHEMBL2158012 | 0.73 | KDM4E (0.70) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL2158406 | 0.71 | KDM4E (0.65) | KDM4EHTTATMMAPTALDH1A1 | |
| SCHEMBL13093718 | 0.69 | KDM4E (0.63) | KDM4EHTTATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |