Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | LPL | P06858 | 12/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744209 | 0.85 | LPL (0.49) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL2426973 | 0.85 | LPL (0.49) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL31469579 | 0.83 | LPL (0.45) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL2428561 | 0.83 | LPL (0.45) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL2316680 | 0.83 | DGAT1 (0.47) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL3803828 | 0.83 | DGAT1 (0.44) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL14873045 | 0.82 | DGAT1 (0.49) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL23816604 | 0.81 | DGAT1 (0.45) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL15941165 | 0.81 | DGAT1 (0.42) | DGAT1LPLLIPGF11FFAR1 | |
| SCHEMBL30064074 | 0.81 | DGAT1 (0.45) | DGAT1LPLLIPGF11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394965-B | Triazolopyridine compound and preparation method and application thereof | 深圳市乐土生物医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-114394965-A | Triazolopyridine compound and preparation method and application thereof | 深圳市乐土生物医药有限公司 | 2022-04-26 | — | — | CN | disclosed |