Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27731025 | 0.95 | MCL1 (0.48) | MCL1FFAR1FFAR4PTPN11MEN1 | |
| SCHEMBL28774631 | 0.90 | PTPN11 (0.49) | MCL1PTPN11MEN1MAPTKMT2A | |
| SCHEMBL27710721 | 0.85 | KMT2A (0.45) | FFAR1PTPN11MEN1KMT2ASIRT2 | |
| SCHEMBL27710533 | 0.81 | LMNA (0.47) | PTPN11MEN1MAPTKMT2ANR1I2 | |
| SCHEMBL27730967 | 0.80 | MEN1 (0.46) | MCL1PTPN11MEN1MAPTKMT2A | |
| SCHEMBL201612 | 0.79 | MEN1 (0.54) | MCL1PTPN11MEN1MAPTKMT2A | |
| SCHEMBL201493 | 0.79 | MEN1 (0.54) | MCL1PTPN11MEN1MAPTKMT2A | |
| SCHEMBL204373 | 0.79 | MEN1 (0.54) | MCL1PTPN11MEN1MAPTKMT2A | |
| SCHEMBL27731118 | 0.79 | LMNA (0.54) | PTPN11MEN1MAPTKMT2ANR1I2 | |
| SCHEMBL27731003 | 0.79 | LMNA (0.51) | MCL1PTPN11MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | claimed |
| CN-101186586-B | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY | 2010-06-30 | — | — | CN | disclosed |
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | disclosed |