Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27730966 | 0.94 | LMNA (0.46) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27731010 | 0.90 | LMNA (0.51) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27730976 | 0.84 | LMNA (0.46) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27731023 | 0.81 | LMNA (0.58) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27940784 | 0.80 | MEN1 (0.52) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL28770640 | 0.79 | MCL1 (0.54) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27730967 | 0.79 | MEN1 (0.46) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27710512 | 0.78 | IRAK4 (0.54) | RORCMKNK1MKNK2 | |
| SCHEMBL27731118 | 0.78 | LMNA (0.54) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL27730999 | 0.77 | LMNA (0.57) | LMNAMEN1NR1I2CHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | claimed |
| CN-101186586-B | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY | 2010-06-30 | — | — | CN | disclosed |
| CN-101186586-A | N,N'-difluorophenyl derivative of 4-methoxyl-1,3-phthalamide and use thereof | UNIV TIANJIN TECHNOLOGY (CN) | 2008-05-28 | — | — | CN | disclosed |