Chloromethane

Chloromethane

SCHEMBL2877103

C=CC(=O)NCCCN(CC)CC.CCl

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
ZDHHC20 Q5W0Z9 1/20 0.56
ZDHHC2 Q9UIJ5 1/20 0.56
PAOX Q6QHF9 1/20 0.42
GAA P10253 3/20 0.42
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPK1 P28482 3/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 3/20 0.40
ALOX15 P16050 1/20 0.39
HTT P42858 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ACKR3 P25106 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109564 0.96 ALDH1A1 (0.65) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
Hydrochloric Acid SCHEMBL29008140 0.95 ALDH1A1 (0.63) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL110266 0.91 ZDHHC20 (0.62) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL7629628 0.90 ALDH1A1 (0.58) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL28545163 0.90 ZDHHC20 (0.66) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL113157 0.90 ZDHHC20 (0.66) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL510803 0.90 ZDHHC20 (0.66) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
Chloromethane SCHEMBL2876687 0.89 ZDHHC20 (0.50) ALDH1A1ZDHHC20ZDHHC2GAAKDM4E
Trimethylammonium SCHEMBL8072751 0.89 ALDH1A1 (0.56) ALDH1A1ZDHHC20ZDHHC2PAOXGAA
SCHEMBL4975704 0.88 ZDHHC20 (0.59) ALDH1A1ZDHHC20ZDHHC2PAOXGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1584633-B1 MODIFIED POLYALLYLAMINE AND PROCESS FOR PRODUCING THE SAME NITTO BOSEKI CO LTD (JP) 2010-10-20 EP disclosed
US-7547747-B2 Modified polyallylamine and process for producing the same NITTO BOSEKI CO., LTD. (JP) 2009-06-16 US disclosed
US-20060122335-A1 Modified polyallylamine and process for producing the same NITTO BOSEKI CO., LTD. (JP) 2006-06-08 US disclosed
EP-1584633-A1 MODIFIED POLYALLYLAMINE AND PROCESS FOR PRODUCING THE SAME NITTO BOSEKI CO., LTD. (JP) 2005-10-12 EP disclosed