Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.62 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.60 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.57 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088653 | 0.86 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5088647 | 0.86 | MAPT (0.62) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6715026 | 0.83 | MAPT (0.68) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6715024 | 0.83 | MAPT (0.68) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL27697050 | 0.83 | MAOB (0.56) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4254944 | 0.82 | ABCG2 (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4254947 | 0.82 | ABCG2 (0.90) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29011937 | 0.82 | MAPT (0.67) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15807361 | 0.82 | MAPT (0.75) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15807393 | 0.81 | NFE2L2 (0.68) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101143861-A | B ring 4'-single substituted flavone compounds, preparation method and use | SHANGHAI INST MATERIA MEDICA (CN) | 2008-03-19 | — | — | CN | disclosed |