SCHEMBL29011937

SCHEMBL29011937

COc1cc(OC)c(C(=O)/C=C/c2ccccc2)cc1C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.67
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
ABCG2 Q9UNQ0 5/20 0.60
NPSR1 Q6W5P4 1/20 0.59
CYP1A1 P04798 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP1B1 Q16678 1/20 0.59
TNFRSF1A P19438 3/20 0.58
NFE2L2 Q16236 1/20 0.57
LMNA P02545 1/20 0.56
RECQL P46063 1/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CAPN1 P07384 1/20 0.55
PARP1 P09874 1/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29011897 0.89 MAPT (0.64) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL29011912 0.87 ABCG2 (0.72) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL6715024 0.87 MAPT (0.68) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL6715026 0.87 MAPT (0.68) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL29011898 0.86 CTSL (0.68) MAPTMEN1KMT2AABCG2TNFRSF1A
SCHEMBL15807393 0.85 NFE2L2 (0.68) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL31412221 0.83 MAPT (0.64) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL29011895 0.83 TNFRSF1A (0.67) MAPTABCG2CYP1A1CYP1A2CYP1B1
SCHEMBL15807361 0.83 MAPT (0.75) MAPTNPC1RAB9AMEN1KMT2A
SCHEMBL997194 0.82 MAPT (0.62) MAPTNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023247-A 2-propylene-1 ketone compound and preparation method and application thereof 暨南大学 2023-04-28 CN claimed
CN-116023247-A 2-propylene-1 ketone compound and preparation method and application thereof 暨南大学 2023-04-28 CN disclosed