Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870662 | 0.87 | TRPV1 (0.32) | HPGDALDH1A1RAB9AGAANPSR1 | |
| SCHEMBL2877113 | 0.85 | PTPRF (0.36) | HPGDALDH1A1RAB9AMAPTKDM4E | |
| SCHEMBL3807257 | 0.84 | KDM4E (0.39) | HPGDALDH1A1RAB9AGAANPSR1 | |
| SCHEMBL2873884 | 0.84 | KDM4E (0.44) | HPGDALDH1A1RAB9AGAAMAPT | |
| SCHEMBL3809145 | 0.82 | TRPV1 (0.38) | HPGDALDH1A1RAB9AGAANPSR1 | |
| SCHEMBL3809451 | 0.81 | NPSR1 (0.40) | NPSR1KDM4EHSD17B10HTTATM | |
| SCHEMBL3816814 | 0.81 | KDM4E (0.39) | HPGDALDH1A1RAB9AGAANPSR1 | |
| SCHEMBL3809123 | 0.81 | NPSR1 (0.40) | NPSR1KDM4EHSD17B10HTTATM | |
| SCHEMBL3811209 | 0.81 | TRPV1 (0.37) | HPGDALDH1A1RAB9AGAANPSR1 | |
| SCHEMBL3812117 | 0.80 | HSD17B1 (0.39) | RAB9ANPSR1MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |