Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811154 | 0.91 | TRPV1 (0.37) | TRPV1TRPM8KDM4EHTTATM | |
| SCHEMBL3809541 | 0.91 | TRPV1 (0.37) | TRPV1TRPM8KDM4EHTTATM | |
| SCHEMBL3811193 | 0.91 | TRPV1 (0.37) | TRPV1TRPM8KDM4EHTTATM | |
| SCHEMBL3809145 | 0.89 | TRPV1 (0.38) | TRPV1TRPM8KDM4EHTTATM | |
| SCHEMBL3807257 | 0.88 | KDM4E (0.39) | TRPV1KDM4EHTTATMUSP30 | |
| SCHEMBL2877207 | 0.87 | TRPV1 (0.42) | TRPV1TRPM8KDM4EHTTATM | |
| SCHEMBL2158215 | 0.86 | PTPRF (0.36) | TRPV1KDM4EHTTATMMAPT | |
| SCHEMBL3814603 | 0.85 | TRPV1 (0.35) | TRPV1KDM4EHTTATMUSP30 | |
| SCHEMBL2879577 | 0.84 | GPR88 (0.33) | TRPV1TRPM8GPR88 | |
| SCHEMBL2874197 | 0.83 | IKBKB (0.35) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |