Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110176 | 0.93 | CYP2C9 (0.42) | KCNN4KCNA3HTR2AHTR2COPRK1 | |
| SCHEMBL13940364 | 0.93 | RAB9A (0.39) | KCNN4KCNA3HTR2AHTR2COPRK1 | |
| SCHEMBL26348876 | 0.83 | KIF11 (0.42) | KIF11KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL20829082 | 0.83 | KIF11 (0.42) | KIF11KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL23110164 | 0.83 | KIF11 (0.42) | KIF11KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL5053673 | 0.83 | KIF11 (0.45) | KCNN4KCNA3HTR2AHTR2COPRK1 | |
| SCHEMBL1096837 | 0.82 | KCNN4 (0.47) | KCNN4KIF11CYP1A2KMT2ACYP2C19 | |
| SCHEMBL3401873 | 0.81 | KCNN4 (0.38) | KCNN4CYP1A2KMT2ACYP2C19HIF1A | |
| SCHEMBL2406465 | 0.81 | KCNN4 (0.42) | KCNN4KCNA3HTR2AHTR2COPRK1 | |
| SCHEMBL28773038 | 0.80 | KCNH2 (0.40) | KCNN4KCNA3HTR2AHTR2COPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729006-A | Cyclic peptide compounds having Kras inhibitory activity | 中外制药株式会社 | 2022-07-08 | — | — | CN | disclosed |