Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745086 | 0.84 | PSIP1 (0.35) | PTPN1PSIP1LOXL2CA5ACSNK2A1 | |
| SCHEMBL14564765 | 0.79 | KDM4E (0.51) | PTPN1KDM4ESMN1; SMN2CA5ACA12 | |
| SCHEMBL2894644 | 0.79 | CA1 (0.47) | KDM4ECA1CA2CA9 | |
| SCHEMBL10149308 | 0.78 | PDCD1 (0.47) | KDM4ECA2 | |
| SCHEMBL14873048 | 0.73 | PTGDR2 (0.42) | PTPN1KDM4E | |
| SCHEMBL30422165 | 0.73 | EPHX1 (0.39) | KDM4ECA5ACA12CA1CA2 | |
| SCHEMBL645987 | 0.73 | EPHX1 (0.39) | KDM4ECA5ACA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL4968998 | 0.72 | PTPN1 (0.38) | PTPN1CSNK2A1CA1CA2CA9 | |
| SCHEMBL14862722 | 0.71 | GAA (0.36) | PTPN1KDM4ECA1CA2CA9 | |
| Hydrogen Sulfide SCHEMBL28158762 | 0.71 | PSIP1 (0.47) | PSIP1KDM4ESMN1; SMN2LOXL2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101336235-A | 1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors | NOVARTIS AG (CH) | 2008-12-31 | — | — | CN | disclosed |