Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394705 | 0.83 | ASH1L (0.52) | ASH1LNPC1PDGFRBEIF2AK2PARP1 | |
| SCHEMBL28773725 | 0.77 | ALDH1A1 (0.43) | NR4A2GPR84 | |
| SCHEMBL145474 | 0.75 | ASH1L (0.72) | ASH1LNPC1PDGFRBEIF2AK2PARP1 | |
| SCHEMBL28773698 | 0.74 | KDM4E (0.50) | NPC1PDGFRBRAB9AHTR6 | |
| SCHEMBL20374476 | 0.73 | SETD7 (0.50) | — | |
| SCHEMBL145745 | 0.73 | ASH1L (0.62) | ASH1LNPC1PDGFRBEIF2AK2PARP1 | |
| SCHEMBL8484407 | 0.73 | ASH1L (0.62) | ASH1LNPC1PDGFRBEIF2AK2KIF11 | |
| SCHEMBL30159619 | 0.72 | NPC1 (0.63) | ASH1LNPC1EIF2AK2PARP1KIF11 | |
| SCHEMBL1553838 | 0.72 | NPC1 (0.63) | ASH1LNPC1EIF2AK2PARP1KIF11 | |
| SCHEMBL6418495 | 0.72 | NR4A2 (0.72) | ASH1LNPC1EIF2AK2PARP1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117246-B | Preparation method of 3-position indolylated cyclohexenone compound | 山西大学 | 2022-05-31 | — | — | CN | disclosed |