Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.36 |
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biguanide SCHEMBL6050569 | 0.87 | NOS3 (0.39) | NOS3NOS1NOS2CYP1A2CYP2D6 | |
| Biguanide SCHEMBL27671000 | 0.87 | TSHR (0.40) | NOS3NOS1NOS2CYP1A2CYP2D6 | |
| Biguanide SCHEMBL8719175 | 0.83 | MAPT (0.36) | NOS1CYP1A2TSHRCYP2C19TDP1 | |
| Biguanide SCHEMBL27454502 | 0.82 | — | — | |
| Biguanide SCHEMBL18255803 | 0.82 | MAPK1 (0.31) | NOS3NOS1NOS2MAPK1 | |
| Biguanide SCHEMBL8039 | 0.82 | — | — | |
| Biguanide SCHEMBL25340958 | 0.81 | SPHK1 (0.52) | NOS3NOS1NOS2TSHRSPHK2 | |
| Biguanide SCHEMBL27598593 | 0.81 | SPHK1 (0.52) | NOS3NOS1NOS2TSHRSPHK2 | |
| SCHEMBL20067144 | 0.81 | — | — | |
| Biguanide SCHEMBL27874285 | 0.81 | TP53 (0.47) | NOS3NOS1NOS2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114561046-B | Guanidine hyaluronic acid type antibacterial hydrogel and preparation method and application thereof | 江南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-114561046-A | Guanidine-based hyaluronic acid type antibacterial hydrogel and preparation method and application thereof | 江南大学 | 2022-05-31 | — | — | CN | disclosed |