Biguanide

Biguanide

SCHEMBL8039

N=C(N)NC(=N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biguanide SCHEMBL18255803 1.00 MAPK1 (0.31)
Biguanide SCHEMBL31013828 0.95
Biguanide SCHEMBL5489883 0.95
Biguanide SCHEMBL28879210 0.95
Biguanide SCHEMBL4217126 0.95
Biguanide SCHEMBL1428352 0.95
Biguanide SCHEMBL4221594 0.95
Biguanide SCHEMBL675101 0.95
Biguanide SCHEMBL10881314 0.95
Biguanide SCHEMBL30340358 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 87495 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117298880-B High-desalination polyamide reverse osmosis membrane and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122031285-A Antibacterial mite-removing bath cream for pets and preparation method thereof 肇庆巧巧日用化工有限公司 2026-05-15 CN claimed
US-20260130633-A1 SYSTEM AND METHOD FOR PREDICTING DISEASE RISK IN FEMALE TAIPEI MEDICAL UNIVERSITY (TW) 2026-05-14 US claimed
US-12624116-B2 Methods of treating severe insulin resistance by interfering with glucagon receptor signaling REGENERON PHARMACEUTICALS, INC. (US) 2026-05-12 US claimed
CN-122013590-A Polymer waterproof antibacterial coating packing box corrugated paper and preparation method thereof 浙江巨鼎包装有限公司 2026-05-12 CN claimed
US-20260124128-A1 COMPOSITION COMPRISING LARGE AMOUNT OF POLYOL L'OREAL (FR) 2026-05-07 US claimed
US-20260126021-A1 FILTER MEDIUM AND METHOD OF PRODUCTION THEREOF NEENAH GESSNER GMBH (DE) 2026-05-07 US claimed
EP-4384082-B1 SYSTEMS, KITS, AND METHODS FOR COATING SUTURES WITH MEDICINAL COMPOUNDS IMMEDIATELY PRIOR TO SUTURE IMPLANTATION ETHICON INC (US) 2026-05-06 EP claimed
EP-4499765-B1 COMPOSITIONS AND METHODS FOR TUNGSTEN ETCHING INHIBITION BASF SE (DE) 2026-05-06 EP claimed
EP-4734978-A2 COMBINATION THERAPIES USING PSILOCYBIN University of Padova (IT) 2026-05-06 EP claimed
US-4253971-A APPLYING BIGUANIDE POLYMER, ALGICIDE ZENECA, INC. 1981-03-03 US claimed
US-4235819-A Process for isolating 1-(alkoxyphenyl)-5-(phenyl)biguanide compounds from a crude, acid reaction mixture thereof GAF CORPORATION (US) 1980-11-25 US claimed
EP-0002042-B1 DIAMINO-1,3,5-TRIAZINYLSTILBENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-29 EP claimed
US-4224245-A Method of making 1-(alkoxyphenyl)-5-(phenyl)biguanide compounds which are useful as agricultural fungicides GAF CORPORATION (US) 1980-09-23 US claimed
US-4196189-A Dental and oral hygiene preparations BLENDAX-WERKE R. SCHNEIDER (DE) 1980-04-01 US claimed
US-4169885-A DENTAL AND ORAL HYGIENE PREPARATIONS BLENDAX-WERKE R. SCHNEIDER GMBH & CO. (DE) 1979-10-02 US claimed
US-4097458-A BIGUANIDE, DI-O-TOLYLBIGUANIDE, DICYANODIAMIDE, OR ARGININE COMPLEXING AGENT USED TO TERMINATE REACTION GENERAL ELECTRIC COMPANY (US) 1978-06-27 US claimed
US-4066462-A PAINTS DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JA) 1978-01-03 US claimed
US-3984537-A DENTIFRICES CONTAINING ANTIBACTERIAL AGENTS COLGATE-PALMOLIVE COMPANY (US) 1976-10-05 US claimed
US-3960949-A DIABETES SCHERING AKTIENGESELLSCHAFT (DT) 1976-06-01 US claimed