Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5259233 | 0.86 | IMPDH2 (0.42) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL394651 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL187169 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1CCNT1CDK9HASPIN | |
| SCHEMBL30665808 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL6600237 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL10095346 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL28239711 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL578797 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| SCHEMBL13181942 | 0.78 | IMPDH2 (0.56) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL29483665 | 0.76 | IMPDH2 (0.55) | IMPDH2IMPDH1DYRK1ACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101219986-B | 3-cyanogen radical indole compounds and its synthetic method | SHANGHAI CHEMPARTNER CO LTD | 2011-08-10 | — | — | CN | disclosed |
| CN-101219986-A | 3-cyanogen radical indole compounds and its synthetic method | SHANGHAI CHEMPARTNER CO LTD (CN) | 2008-07-16 | — | — | CN | disclosed |