Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30886193 | 0.94 | PKM (0.40) | GPR119MEN1KMT2AHPGDPKM | |
| SCHEMBL16757588 | 0.94 | PKM (0.40) | GPR119MEN1KMT2AHPGDPKM | |
| SCHEMBL30944812 | 0.89 | GPR119 (0.40) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL30944813 | 0.89 | GPR119 (0.40) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL17322784 | 0.88 | GPR119 (0.40) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL28774248 | 0.84 | KMT2A (0.37) | GPR119MEN1KMT2APKMSTS | |
| SCHEMBL28504795 | 0.84 | GPR119 (0.34) | GPR119MEN1KMT2AHPGDPKM | |
| SCHEMBL28504794 | 0.84 | GPR119 (0.34) | GPR119MEN1KMT2AHPGDPKM | |
| SCHEMBL30886242 | 0.81 | PKM (0.36) | PKMPDE3BPDE3A | |
| SCHEMBL21836126 | 0.81 | GPR119 (0.35) | GPR119MEN1KMT2AHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641283-B | Anti-CD 25 antibody-maytansine conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114641283-A | anti-CD 25 antibody-maytansine conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-114599402-A | anti-CD 37 antibody-maytansine conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2022-06-07 | — | — | CN | disclosed |