Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.47 |
| ▸ | TUBB | P07437 | 4/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28774635 | 0.84 | TUBB4A (0.49) | ALDH1A1KDM4EMAPTTUBB4ATUBB | |
| SCHEMBL28774640 | 0.82 | CYP1A2 (0.44) | ALDH1A1KDM4EMAPTTSHRTUBB4A | |
| SCHEMBL10785938 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EMAPTHPGDPTAFR | |
| SCHEMBL28774637 | 0.80 | CYP1A1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28774650 | 0.78 | TUBB4A (0.55) | ALDH1A1KDM4EMAPTTUBB4ATUBB | |
| SCHEMBL29086514 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29689549 | 0.77 | KDM1A (0.49) | ALDH1A1KDM4EMAPTTSHRTUBB4A | |
| SCHEMBL28774645 | 0.77 | KDM1A (0.49) | ALDH1A1KDM4EMAPTTSHRTUBB4A | |
| SCHEMBL29689393 | 0.77 | KDM1A (0.49) | ALDH1A1KDM4EMAPTTSHRTUBB4A | |
| SCHEMBL28774660 | 0.77 | KDM1A (0.49) | ALDH1A1KDM4EMAPTTSHRTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573490-A | diaryl-2H-aziridines and diaryl aziridines compounds, preparation method and application thereof | 复旦大学 | 2022-06-03 | — | — | CN | disclosed |