Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143990 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL3902453 | 0.86 | KMT2A (0.73) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL2957229 | 0.83 | KMT2A (0.54) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| Dinitrophenylene SCHEMBL27738113 | 0.80 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL2955716 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL1248559 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL6796308 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMAPTMEN1HTT | |
| SCHEMBL31405188 | 0.79 | HSP90AA1 (0.77) | KMT2AHTTLMNAALDH1A1HSP90AA1 | |
| SCHEMBL11356136 | 0.79 | HSP90AA1 (0.77) | KMT2AHTTLMNAALDH1A1HSP90AA1 | |
| SCHEMBL20591230 | 0.78 | HSP90AA1 (0.61) | SMN1; SMN2KMT2AMAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384592-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |