Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 13/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590056 | 0.90 | EIF4E (0.44) | EIF4EMEN1KMT2ACYP19A1CYP11B1 | |
| SCHEMBL3580015 | 0.77 | EIF4E (0.47) | EIF4ELMNAMAPTRECQLMEN1 | |
| SCHEMBL28780443 | 0.75 | CTSV (0.45) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1446807 | 0.74 | EIF4E (0.42) | EIF4ECYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3581595 | 0.73 | POLB (0.47) | NPC1RAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL1447240 | 0.72 | POLB (0.46) | NPC1RAB9AMAPTPOLBNFKB1 | |
| SCHEMBL2685823 | 0.72 | CYP11B1 (0.63) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL3598965 | 0.72 | MEN1 (0.49) | EIF4ENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3581708 | 0.72 | TUBB4A (0.41) | NPC1RAB9AMEN1KMT2ACYP19A1 | |
| SCHEMBL27764455 | 0.71 | POLB (0.39) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454285-B | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA | 2012-06-27 | — | — | CN | disclosed |
| CN-101454285-A | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA (PT) | 2009-06-10 | — | — | CN | disclosed |