Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120279 | 0.87 | HSD17B10 (0.33) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL30861987 | 0.87 | HSD17B10 (0.33) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL31234561 | 0.87 | HSD17B10 (0.33) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL5183988 | 0.87 | HSD17B10 (0.33) | MEN1ALDH1A1MAPTKMT2ANR1H2 | |
| SCHEMBL22367426 | 0.85 | DPP4 (0.39) | DPP4FAP | |
| SCHEMBL17180203 | 0.82 | UCHL1 (0.39) | DPP4ARCTSKMEN1ALDH1A1 | |
| SCHEMBL17180202 | 0.82 | UCHL1 (0.39) | DPP4ARCTSKMEN1ALDH1A1 | |
| SCHEMBL4300617 | 0.82 | UCHL1 (0.37) | ALDH1A1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL4300613 | 0.82 | UCHL1 (0.37) | ALDH1A1NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL2080406 | 0.81 | ALDH1A1 (0.36) | ARCTSKMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794422-B | Heterocyclic compounds as PD-L1 inhibitors | 南京圣和药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |