Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868557 | 0.88 | CYP3A4 (0.33) | BDKRB2CYP3A4CYP2C19MRGPRX4ADORA2A | |
| SCHEMBL2872758 | 0.88 | BDKRB2 (0.46) | BDKRB2CYP3A4CYP2C19MRGPRX4 | |
| SCHEMBL2875012 | 0.87 | BDKRB2 (0.34) | BDKRB2CYP3A4CYP2C19MRGPRX4 | |
| SCHEMBL2878108 | 0.86 | BDKRB2 (0.45) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL1564444 | 0.85 | BDKRB2 (0.48) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL2877603 | 0.85 | BDKRB2 (0.40) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL2878084 | 0.85 | BDKRB2 (0.34) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL2877380 | 0.85 | BDKRB2 (0.40) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL13093261 | 0.81 | BDKRB2 (0.48) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL2879546 | 0.80 | BDKRB2 (0.33) | BDKRB2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144897-B1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2010-10-20 | — | — | EP | claimed |