Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 17/20 | 0.45 |
| ▸ | EDNRB | P24530 | 13/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017673 | 0.85 | EDNRB (0.43) | EDNRAEDNRBSCN9AMAPTKMT2A | |
| SCHEMBL727644 | 0.84 | CFTR (0.40) | EDNRAEDNRBMAPTMAPK1KMT2A | |
| SCHEMBL28523565 | 0.80 | KMT2A (0.44) | EDNRASCN9AKMT2A | |
| Benzoic Acid SCHEMBL28982995 | 0.76 | GAA (0.43) | MAPK1KMT2A | |
| SCHEMBL3197538 | 0.73 | EDNRA (0.44) | EDNRAEDNRBMAPTRAB9AKMT2A | |
| SCHEMBL27617469 | 0.71 | KMT2A (0.39) | EDNRAEDNRBKMT2A | |
| Cinnamic Acid SCHEMBL28983011 | 0.71 | HCAR2 (0.47) | NPC1MAPTMAPK1RAB9AKMT2A | |
| SCHEMBL5583991 | 0.70 | CHRM3 (0.46) | SCN9ANPC1MAPTMAPK1RAB9A | |
| SCHEMBL30825751 | 0.70 | CHRM3 (0.46) | SCN9ANPC1MAPTMAPK1RAB9A | |
| SCHEMBL31086937 | 0.67 | MAPT (0.47) | EDNRAEDNRBNPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641183-B | Prevention and treatment of vascular calcification and cardiovascular/related diseases | 顶峰创新实验室有限公司 | 2022-07-12 | — | — | CN | disclosed |