SCHEMBL727644

SCHEMBL727644

O=C1C(O)(O)c2ccccc2OC1(O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.40
GOPC Q9HD26 1/20 0.40
CYP3A4 P08684 3/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.36
MAPK1 P28482 1/20 0.36
MEN1 O00255 2/20 0.35
ALOX15 P16050 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP2D6 P10635 1/20 0.35
GAA P10253 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSP90AA1 P07900 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
AKR1B1 P15121 1/20 0.33
PKM P14618 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL28982995 0.91 GAA (0.43) CFTRGOPCCYP3A4CYP2C9CYP2C19
Cinnamic Acid SCHEMBL28983011 0.85 HCAR2 (0.47) CYP2C9MAPK1MEN1KMT2ACYP2D6
SCHEMBL28777828 0.84 EDNRA (0.45) MAPK1KMT2AEDNRBEDNRAMAPT
SCHEMBL29017673 0.80 EDNRB (0.43) CYP3A4CYP2C9MEN1KMT2AGAA
SCHEMBL3698502 0.79 CA1 (0.33) CFTRGOPCCYP3A4MAPK1MEN1
SCHEMBL4654217 0.78 DBH (0.35) CYP3A4MAPK1MEN1ALOX15KMT2A
SCHEMBL28523565 0.76 KMT2A (0.44) CYP3A4CYP2C9KMT2AEDNRAATM
SCHEMBL27617469 0.73 KMT2A (0.39) CYP3A4CYP2C9CYP2C19KMT2ANPSR1
SCHEMBL27441451 0.72 PLK1 (0.35) CYP3A4CYP2C9CYP2C19MAPK1MEN1
SCHEMBL11113199 0.71 CFTR (0.42) CFTRGOPCCYP3A4MEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119320777-A Metabolite screening method for promoting expression of porcine intestinal defensin pBD1 and application thereof 浙江大学 2025-01-17 CN claimed
US-20240301326-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt Benckiser Health Limited (GB) 2024-09-12 US claimed
EP-4373906-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-05-29 EP claimed
CN-117716012-A Cage-free self-adhesive toilet cleaning composition 雷克特和科尔曼(海外)家用卫生有限公司 2024-03-15 CN claimed
US-20230248755-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH BioRelief, LLC (US) 2023-08-10 US claimed
CN-115787325-A Polyester low-temperature dyeing accelerant and preparation method thereof 太仓宝霓实业有限公司 2023-03-14 CN claimed
WO-2023002214-A1 CAGELESS SELF-ADHESIVE LAVATORY CLEANING COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2023-01-26 WO claimed
US-20210060048-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH BIORELIEF LLC (US) 2021-03-04 US claimed
CN-105866445-A Liquid-phase thrombin time determining reagent and preparation method thereof 青岛古高生物科技有限公司 2016-08-17 CN claimed
WO-2013079187-A9 TASTE-MASKING COMPOSITIONS, SWEETENER COMPOSITIONS AND CONSUMABLE PRODUCT COMPOSITIONS CONTAINING THE SAME NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) 2016-04-14 WO claimed
EP-1429602-A4 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS UNIV RUTGERS (US) 2005-12-21 EP claimed
US-20050069598-A1 Methods for treating disorders using plant extracts RIBNICKY DAVID M (US) 2005-03-31 US claimed
JP-2005505544-A 2005-02-24 JP claimed
US-20040180800-A1 Cleaning and protecting composition with antioxidant and UV light resistance and method of use HOMECARE LABS, INC. 2004-09-16 US claimed
EP-1429602-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2004-06-23 EP claimed
US-20030072822-A1 Methods for treating disorders using plant extracts RUTGERS, THE STATE OF UNIVERSITY OF NEW JERSEY 2003-04-17 US claimed
WO-2003020026-A1 METHODS FOR TREATING DISORDERS USING PLANT EXTRACTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2003-03-13 WO claimed
EP-1067913-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS Bioresponse, L.L.C. (US) 2001-01-17 EP claimed
WO-1999049851-A1 COMPOSITIONS AND METHODS OF ADJUSTING STEROID HORMONE METABOLISM THROUGH FACILITATED ABSORPTION OF HYDROPHOBIC DIETARY COMPOUNDS BIORESPONSE, L.L.C. (US) 1999-10-07 WO claimed
EP-0245931-A2 Nodulation inducing factors LUBRIZOL GENETICS INC. (US) 1987-11-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210060048-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH TRPV1, CALCB, TRPV2 CFTR 410/4885GOPC 2125/4885CYP3A4 4406/4885
US-20230248755-A1 COMPOSITIONS FOR IMPROVING JOINT HEALTH TRPV1, CALCB, TRPV2 CFTR 410/4885GOPC 2125/4885CYP3A4 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.