SCHEMBL28523565

SCHEMBL28523565

COc1ccccc1C1(O)Oc2ccccc2C(O)(O)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
EDNRA P25101 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
SCN9A Q15858 1/20 0.36
PDK2 Q15119 1/20 0.35
OPRM1 P35372 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
OPRL1 P41146 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28777828 0.80 EDNRA (0.45) KMT2AEDNRASCN9A
SCHEMBL29017673 0.77 EDNRB (0.43) KMT2AEDNRACA1CA2CA7
SCHEMBL727644 0.76 CFTR (0.40) KMT2AEDNRACYP3A4CYP2C9OPRM1
SCHEMBL4654217 0.75 DBH (0.35) KMT2ACA1CA2CA7CA9
SCHEMBL13424205 0.71 CA1 (0.44) KMT2ASIGMAR1CA1CA2CA7
Benzoic Acid SCHEMBL28982995 0.70 GAA (0.43) KMT2ACYP3A4CYP2C9PDK2OPRD1
SCHEMBL8121148 0.67 KMT2A (0.43) KMT2ASIGMAR1CA1CA2CA7
SCHEMBL11111518 0.67 PDK2 (0.43) KMT2ASIGMAR1CA1CA2CA7
SCHEMBL6239972 0.66 CYP19A1 (0.42) KMT2ASIGMAR1CA1CA2CA7
SCHEMBL12261434 0.66 CA1 (0.39) KMT2ASIGMAR1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209911-B Flavonoid component in fine She Yuanwei and antioxidant activity thereof 中国药科大学 2023-12-01 CN disclosed
CN-112209911-A Flavonoid component in Iris tenuifolia and its antioxidant activity 中国药科大学 2021-01-12 CN disclosed